BDBM50097702 CHEMBL3590198
SMILES Cc1cc(C)c(c(C)c1)S(=O)(=O)N1CCc2cc(ccc2C1)C(=O)NCCN(Cc1ccc(F)cc1)C(C)(C)C
InChI Key InChIKey=FIAVSELVAMSPBT-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50097702
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center
Curated by ChEMBL
University Of Kansas Specialized Chemistry Center
Curated by ChEMBL
Affinity DataIC50: 85nMAssay Description:Antagonist activity against HA-tagged human recombinant kappa opioid receptor expressed in CHO cell membranes incubated for 1 hr by [35S]GTPgammaS bi...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center
Curated by ChEMBL
University Of Kansas Specialized Chemistry Center
Curated by ChEMBL
Affinity DataIC50: 880nMAssay Description:Antagonist activity against human kappa opioid receptor expressed in human U2OS cells co-expressing beta-arrestin2 pre-treated for 15 mins before U69...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center
Curated by ChEMBL
University Of Kansas Specialized Chemistry Center
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Antagonist activity against HA-tagged human recombinant kappa opioid receptor expressed in CHO cells assessed as inhibition of U69,593-induced ERK ph...More data for this Ligand-Target Pair