BDBM50098490 4-(4-Trifluoromethyl-phenylsulfanyl)-thieno[2,3-c]pyridine-2-carboxylic acid amide::CHEMBL6542

SMILES NC(=O)c1cc2c(Sc3ccc(cc3)C(F)(F)F)cncc2s1

InChI Key InChIKey=VIAAOSSEVPAHGM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50098490   

TargetIntercellular adhesion molecule 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50098490(4-(4-Trifluoromethyl-phenylsulfanyl)-thieno[2,3-c]...)
Affinity DataIC50:  39nMAssay Description:In vitro potency against TNF alpha induced expresion of intercellular adhesion molecule-1 on human vascular endothelial cells using CAM ELISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE-selectin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50098490(4-(4-Trifluoromethyl-phenylsulfanyl)-thieno[2,3-c]...)
Affinity DataIC50:  44nMAssay Description:In vitro potency against TNF alpha induced expression of Selectin E on human vascular endothelial cells using CAM ELISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular cell adhesion protein 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50098490(4-(4-Trifluoromethyl-phenylsulfanyl)-thieno[2,3-c]...)
Affinity DataIC50: >100nMAssay Description:In vitro potency against TNF alpha induced expresion of VCAM-1 on human vascular endothelial cells using CAM ELISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed