BDBM50099664 CHEMBL3319483
SMILES C[C@@H](NC(=O)C1=C(C)c2ccccc2C1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC1CCCCC1)C(=O)[C@@]1(C)CO1
InChI Key InChIKey=ADZWRNLELCYOIA-UHFFFAOYSA-N
Data 12 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50099664
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Leiden Institute Of Chemistry And Netherlands Proteomics Centre
Curated by ChEMBL
Leiden Institute Of Chemistry And Netherlands Proteomics Centre
Curated by ChEMBL
Affinity DataIC50: 8.30nMAssay Description:Inhibition of proteasome subunit beta-5i in human Raji cells using BODIPY-NC005 by fluorescent densitometryMore data for this Ligand-Target Pair
TargetProteasome subunit beta type-9(Homo sapiens (Human))
Leiden Institute Of Chemistry And Netherlands Proteomics Centre
Curated by ChEMBL
Leiden Institute Of Chemistry And Netherlands Proteomics Centre
Curated by ChEMBL
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of proteasome subunit beta-1i in human Raji cells using BODIPY- epoxomicin by fluorescent densitometryMore data for this Ligand-Target Pair
TargetProteasome subunit beta type-10(Homo sapiens (Human))
Leiden Institute Of Chemistry And Netherlands Proteomics Centre
Curated by ChEMBL
Leiden Institute Of Chemistry And Netherlands Proteomics Centre
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of proteasome subunit beta-2i in human Raji cells using BODIPY- epoxomicin by fluorescent densitometryMore data for this Ligand-Target Pair
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Leiden Institute Of Chemistry And Netherlands Proteomics Centre
Curated by ChEMBL
Leiden Institute Of Chemistry And Netherlands Proteomics Centre
Curated by ChEMBL
Affinity DataIC50: 230nMAssay Description:Inhibition of proteasome subunit beta-5i in human RPMI8226 cells using BODIPY-NC005 by fluorescent densitometryMore data for this Ligand-Target Pair
TargetProteasome subunit beta type-9(Homo sapiens (Human))
Leiden Institute Of Chemistry And Netherlands Proteomics Centre
Curated by ChEMBL
Leiden Institute Of Chemistry And Netherlands Proteomics Centre
Curated by ChEMBL
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of proteasome subunit beta-1i in human RPMI8226 cells using BODIPY-NC001 by fluorescent densitometryMore data for this Ligand-Target Pair
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Leiden Institute Of Chemistry
Curated by ChEMBL
Leiden Institute Of Chemistry
Curated by ChEMBL
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of catalytic activity of immunoproteasome 20s subunit beta2 in human Raji cells incubated for 1 hr by BODIPY(FL)-LU-112 probe based compet...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Leiden Institute Of Chemistry
Curated by ChEMBL
Leiden Institute Of Chemistry
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of catalytic activity of immunoproteasome 20s subunit beta5 in human Raji cells incubated for 1 hr by BODIPY(TMR)-NC-005-VS probe based co...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Leiden Institute Of Chemistry
Curated by ChEMBL
Leiden Institute Of Chemistry
Curated by ChEMBL
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of catalytic activity of constitutive proteasome 20s subunit beta5 in human Raji cells incubated for 1 hr by BODIPY(TMR)-NC-005-VS probe b...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Leiden Institute Of Chemistry
Curated by ChEMBL
Leiden Institute Of Chemistry
Curated by ChEMBL
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of catalytic activity of constitutive proteasome 20s subunit beta1 in human Raji cells incubated for 1 hr by Cy5-NC-001 probe based compet...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Leiden Institute Of Chemistry
Curated by ChEMBL
Leiden Institute Of Chemistry
Curated by ChEMBL
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of catalytic activity of immunoproteasome 20s subunit beta1 in human Raji cells incubated for 1 hr by Cy5-NC-001 probe based competitive a...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Leiden Institute Of Chemistry
Curated by ChEMBL
Leiden Institute Of Chemistry
Curated by ChEMBL
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of catalytic activity of constitutive proteasome 20s subunit beta2 in human Raji cells incubated for 1 hr by BODIPY(FL)-LU-112 probe based...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-10(Homo sapiens (Human))
Leiden Institute Of Chemistry And Netherlands Proteomics Centre
Curated by ChEMBL
Leiden Institute Of Chemistry And Netherlands Proteomics Centre
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of proteasome subunit beta-2i in human RPMI8226 cells using BODIPY-epoxomicin by fluorescent densitometryMore data for this Ligand-Target Pair