BDBM50099707 CHEMBL49992::[(9,10-Dioxo-9,10-dihydro-phenanthrene-2-carbonyl)-amino]-acetic acid tert-butyl ester

SMILES CC(C)(C)OC(=O)CNC(=O)c1ccc2-c3ccccc3C(=O)C(=O)c2c1

InChI Key InChIKey=ZSXXRDOSSHHHJO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50099707   

TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099707(CHEMBL49992 | [(9,10-Dioxo-9,10-dihydro-phenanthre...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibitory concentration against PTP1B using lck as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099707(CHEMBL49992 | [(9,10-Dioxo-9,10-dihydro-phenanthre...)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibitory concentration against CD45 protein-tyrosine phosphatase using lck-10mer as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099707(CHEMBL49992 | [(9,10-Dioxo-9,10-dihydro-phenanthre...)
Affinity DataIC50:  600nMAssay Description:In vitro inhibitory activity against the cytosolic portion of CD45 protein-tyrosine phosphatase using pNPP as the substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed