BDBM50099903 4-[4-(3-Methoxy-phenyl)-thiazol-2-yl]-5-methylsulfanyl-thiophene-2-carboxamidine::CHEMBL29205
SMILES COc1cccc(c1)-c1csc(n1)-c1cc(sc1SC)C(N)=N
InChI Key InChIKey=HFUGBKCICWUZIJ-UHFFFAOYSA-N
Data 7 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50099903
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
3-Dimensional Pharmaceuticals
Curated by ChEMBL
3-Dimensional Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 115nMAssay Description:Inhibitory activity against serine protease urokinase-type plasminogen activator (microPa)More data for this Ligand-Target Pair
TargetComplement C1s subcomponent(Homo sapiens (Human))
3-Dimensional Pharmaceuticals
Curated by ChEMBL
3-Dimensional Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 470nMAssay Description:In vitro binding affinity towards human Complement C1s subcomponentMore data for this Ligand-Target Pair
Affinity DataKi: 860nMAssay Description:Inhibitory activity of the compound against TrypsinMore data for this Ligand-Target Pair
TargetTissue-type plasminogen activator(Homo sapiens (Human))
3-Dimensional Pharmaceuticals
Curated by ChEMBL
3-Dimensional Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 1.90E+3nMAssay Description:Inhibitory activity of the compound against tissue plasminogen activatorMore data for this Ligand-Target Pair
Affinity DataKi: 6.90E+3nMAssay Description:Inhibitory activity of the compound against plasminMore data for this Ligand-Target Pair
Affinity DataKi: >3.00E+4nMAssay Description:Inhibitory activity of the compound against Thrombin (no observable inhibition at this screening concentration)More data for this Ligand-Target Pair
Affinity DataKi: >3.00E+4nMAssay Description:Inhibitory activity of the compound against Serine protease chymotrypsin (no observable inhibition at this screening concentration)More data for this Ligand-Target Pair