BDBM50101021 1,4-di[4-(4-aminomethylhexahydro-1-pyridinylcarboxamidomethyl)hexahydro-1-pyridinylcarbonyloxymethyl]benzene::CHEMBL296733

SMILES NCC1CCN(CC1)C(=O)NCC1CCN(CC1)C(=O)OCc1ccc(COC(=O)N2CCC(CNC(=O)N3CCC(CN)CC3)CC2)cc1

InChI Key InChIKey=YYHDIRDOEUMGPH-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50101021   

TargetTryptase beta-2/delta/gamma(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101021(1,4-di[4-(4-aminomethylhexahydro-1-pyridinylcarbox...)
Affinity DataKi:  24nMAssay Description:Binding affinity to 5-HT3 serotonin receptor in NG 108-15 neuroblastoma glioma cells using [3H]-GR-65,630 radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101021(1,4-di[4-(4-aminomethylhexahydro-1-pyridinylcarbox...)
Affinity DataKi:  5.15E+5nMAssay Description:Binding affinity to 5-HT3 serotonin receptor in NG 108-15 neuroblastoma glioma cells using [3H]-GR-65,630 radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101021(1,4-di[4-(4-aminomethylhexahydro-1-pyridinylcarbox...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of thrombin in human mast cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101021(1,4-di[4-(4-aminomethylhexahydro-1-pyridinylcarbox...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition plasmin in human mast cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed