BDBM50101095 CHEMBL3325957
SMILES OC(=O)CC(O)(CC(O)=O)C(O)=O.CN(C)[C@]1(CC[C@@]2(CC1)OCCc1c2[nH]c2ccc(F)cc12)c1ccccc1
InChI Key
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50101095
Affinity DataKi: 0.700nMAssay Description:Displacement of [3H]naloxone from human MOP receptor expressed in CHO-K1 cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO-K1 cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.60nMAssay Description:Binding affinity to human kappa opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Binding affinity to human delta opioid receptorMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S(Rattus norvegicus)
Pharmacokinetics
Curated by ChEMBL
Pharmacokinetics
Curated by ChEMBL
Affinity DataKi: 480nMAssay Description:Inhibition of rat brain cortex L-type Ca2+-channel phenylalkylamine siteMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S(Rattus norvegicus)
Pharmacokinetics
Curated by ChEMBL
Pharmacokinetics
Curated by ChEMBL
Affinity DataKi: 800nMAssay Description:Inhibition of rat brain cortex L-type Ca2+-channel benzothiazepine siteMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S(Rattus norvegicus)
Pharmacokinetics
Curated by ChEMBL
Pharmacokinetics
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of rat whole brain L-type Ca2+-channel dihydropyridine siteMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pharmacokinetics
Curated by ChEMBL
Pharmacokinetics
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
Affinity DataEC50: 1.20nMAssay Description:Agonist activity at human recombinant MOP receptor expressed in CHO-K1 cells assessed as stimulation of [35S]GTPgammaS binding by scintillation proxi...More data for this Ligand-Target Pair
Affinity DataEC50: 13nMAssay Description:Agonist activity at human recombinant NOP receptor expressed in CHO-K1 cells assessed as stimulation of [35S]GTPgammaS binding by scintillation proxi...More data for this Ligand-Target Pair