BDBM50101095 CHEMBL3325957

SMILES OC(=O)CC(O)(CC(O)=O)C(O)=O.CN(C)[C@]1(CC[C@@]2(CC1)OCCc1c2[nH]c2ccc(F)cc12)c1ccccc1

InChI Key

Data  8 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50101095   

TargetMu-type opioid receptor(Homo sapiens (Human))
Pharmacokinetics

Curated by ChEMBL
LigandPNGBDBM50101095(CHEMBL3325957)
Affinity DataKi:  0.700nMAssay Description:Displacement of [3H]naloxone from human MOP receptor expressed in CHO-K1 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Pharmacokinetics

Curated by ChEMBL
LigandPNGBDBM50101095(CHEMBL3325957)
Affinity DataKi:  0.900nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO-K1 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Pharmacokinetics

Curated by ChEMBL
LigandPNGBDBM50101095(CHEMBL3325957)
Affinity DataKi:  2.60nMAssay Description:Binding affinity to human kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Pharmacokinetics

Curated by ChEMBL
LigandPNGBDBM50101095(CHEMBL3325957)
Affinity DataKi:  18nMAssay Description:Binding affinity to human delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50101095(CHEMBL3325957)
Affinity DataKi:  480nMAssay Description:Inhibition of rat brain cortex L-type Ca2+-channel phenylalkylamine siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50101095(CHEMBL3325957)
Affinity DataKi:  800nMAssay Description:Inhibition of rat brain cortex L-type Ca2+-channel benzothiazepine siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50101095(CHEMBL3325957)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of rat whole brain L-type Ca2+-channel dihydropyridine siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pharmacokinetics

Curated by ChEMBL
LigandPNGBDBM50101095(CHEMBL3325957)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Pharmacokinetics

Curated by ChEMBL
LigandPNGBDBM50101095(CHEMBL3325957)
Affinity DataEC50:  1.20nMAssay Description:Agonist activity at human recombinant MOP receptor expressed in CHO-K1 cells assessed as stimulation of [35S]GTPgammaS binding by scintillation proxi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Pharmacokinetics

Curated by ChEMBL
LigandPNGBDBM50101095(CHEMBL3325957)
Affinity DataEC50:  13nMAssay Description:Agonist activity at human recombinant NOP receptor expressed in CHO-K1 cells assessed as stimulation of [35S]GTPgammaS binding by scintillation proxi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed