BDBM50101522 CHEMBL76869::[(S)-2-((S)-2-Cyclohexyl-1-phenethylcarbamoyl-ethylcarbamoyl)-5-p-tolyl-pentyl]-phosphonic acid::[2-(2-Cyclohexyl-1-phenethylcarbamoyl-ethylcarbamoyl)-5-p-tolyl-pentyl]-phosphonic acid

SMILES Cc1ccc(CCC[C@H](CP(O)(O)=O)C(=O)N[C@@H](CC2CCCCC2)C(=O)NCCc2ccccc2)cc1

InChI Key InChIKey=PNOAVGXEWQIVLB-IZLXSDGUSA-N

Data  9 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50101522   

Target72 kDa type IV collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50101522(CHEMBL76869 | [(S)-2-((S)-2-Cyclohexyl-1-phenethyl...)
Affinity DataKi:  2.5nMAssay Description:Inhibition of the Gelatinase-A enzyme was determined from purified NSO cells.More data for this Ligand-Target Pair
In DepthDetails Article
Target72 kDa type IV collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50101522(CHEMBL76869 | [(S)-2-((S)-2-Cyclohexyl-1-phenethyl...)
Affinity DataKi:  2.5nMAssay Description:Inhibition of the Collagenase enzyme was determined from purified NSO cells.More data for this Ligand-Target Pair
In DepthDetails Article
Target72 kDa type IV collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50101522(CHEMBL76869 | [(S)-2-((S)-2-Cyclohexyl-1-phenethyl...)
Affinity DataKi:  2.5nMAssay Description:Inhibitory constant against matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50101522(CHEMBL76869 | [(S)-2-((S)-2-Cyclohexyl-1-phenethyl...)
Affinity DataKi:  277nMAssay Description:Inhibition of the Gelatinase-A enzyme was determined from purified NSO cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50101522(CHEMBL76869 | [(S)-2-((S)-2-Cyclohexyl-1-phenethyl...)
Affinity DataKi:  277nMAssay Description:Inhibition of the Stromelysin enzyme was determined from purified NSO cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50101522(CHEMBL76869 | [(S)-2-((S)-2-Cyclohexyl-1-phenethyl...)
Affinity DataKi:  277nMAssay Description:Inhibitory constant against matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
The Royal Danish School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50101522(CHEMBL76869 | [(S)-2-((S)-2-Cyclohexyl-1-phenethyl...)
Affinity DataKi:  1.70E+3nMAssay Description:Inhibitory constant against matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
The Royal Danish School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50101522(CHEMBL76869 | [(S)-2-((S)-2-Cyclohexyl-1-phenethyl...)
Affinity DataKi:  1.70E+4nMAssay Description:Inhibition of the Stromelysin enzyme was determined from purified NSO cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterstitial collagenase(Homo sapiens (Human))
The Royal Danish School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50101522(CHEMBL76869 | [(S)-2-((S)-2-Cyclohexyl-1-phenethyl...)
Affinity DataKi:  1.70E+4nMAssay Description:Inhibition of the Collagenase enzyme was determined from purified NSO cells.More data for this Ligand-Target Pair
In DepthDetails Article