BDBM50102266 1-(5-Bromo-pyridin-2-yl)-3-[2-(7-fluoro-4-oxo-4H-pyrrolo[1,2-a]quinoxalin-5-yl)-ethyl]-thiourea::CHEMBL418812

SMILES Fc1ccc2c(c1)n(CCNC(=S)Nc1ccc(Br)cn1)c(=O)c1cccn21

InChI Key InChIKey=RASMUIBDADGVHI-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50102266   

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Universita' Degli Studi Di Salerno

Curated by ChEMBL
LigandPNGBDBM50102266(1-(5-Bromo-pyridin-2-yl)-3-[2-(7-fluoro-4-oxo-4H-p...)
Affinity DataKi:  29nMAssay Description:Inhibition of HIV-1 wild-type RTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Universita' Degli Studi Di Salerno

Curated by ChEMBL
LigandPNGBDBM50102266(1-(5-Bromo-pyridin-2-yl)-3-[2-(7-fluoro-4-oxo-4H-p...)
Affinity DataKi:  40nMAssay Description:Inhibition of HIV-1 Mutant HIV-1 RT enzymes containing the single amino acid substitution V106AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Universita' Degli Studi Di Salerno

Curated by ChEMBL
LigandPNGBDBM50102266(1-(5-Bromo-pyridin-2-yl)-3-[2-(7-fluoro-4-oxo-4H-p...)
Affinity DataKi:  650nMAssay Description:Inhibition of HIV-1 Mutant HIV-1 RT enzymes containing the single amino acid substitution K103NMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Universita' Degli Studi Di Salerno

Curated by ChEMBL
LigandPNGBDBM50102266(1-(5-Bromo-pyridin-2-yl)-3-[2-(7-fluoro-4-oxo-4H-p...)
Affinity DataKi:  700nMAssay Description:Inhibition of HIV-1 Mutant HIV-1 RT enzymes containing the single amino acid substitution L1001More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Universita' Degli Studi Di Salerno

Curated by ChEMBL
LigandPNGBDBM50102266(1-(5-Bromo-pyridin-2-yl)-3-[2-(7-fluoro-4-oxo-4H-p...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of HIV-1 Mutant HIV-1 RT enzymes containing the single amino acid substitution Y181IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Universita' Degli Studi Di Salerno

Curated by ChEMBL
LigandPNGBDBM50102266(1-(5-Bromo-pyridin-2-yl)-3-[2-(7-fluoro-4-oxo-4H-p...)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition of HIV-1 Mutant HIV-1 RT enzymes containing the single amino acid substitution Y188LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed