BDBM50102775 2-(2-Hydroxy-4-methyl-phenyl)-1H-benzoimidazole-5-carboxamidine::CHEMBL92865

SMILES Cc1ccc(-c2nc3ccc(cc3[nH]2)C(N)=N)c(O)c1

InChI Key InChIKey=MJALKSPFTYWAAL-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50102775   

TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102775(2-(2-Hydroxy-4-methyl-phenyl)-1H-benzoimidazole-5-...)
Affinity DataKi:  3.60E+3nMAssay Description:ComInhibition of Human Serine Protease Urokinase Plasminogen Activator (u-PA).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102775(2-(2-Hydroxy-4-methyl-phenyl)-1H-benzoimidazole-5-...)
Affinity DataKi:  9.40E+3nMAssay Description:Binding affinity against human coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102775(2-(2-Hydroxy-4-methyl-phenyl)-1H-benzoimidazole-5-...)
Affinity DataKi:  1.80E+4nMAssay Description:Inhibition of Human Serine Protease Trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102775(2-(2-Hydroxy-4-methyl-phenyl)-1H-benzoimidazole-5-...)
Affinity DataKi:  3.50E+4nMAssay Description:Inhibition of Human Serine Protease Plasmin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102775(2-(2-Hydroxy-4-methyl-phenyl)-1H-benzoimidazole-5-...)
Affinity DataKi:  3.80E+4nMAssay Description:Inhibition of Human Serine Protease Thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102775(2-(2-Hydroxy-4-methyl-phenyl)-1H-benzoimidazole-5-...)
Affinity DataKi:  4.80E+4nMAssay Description:Inhibition of Human Serine Protease tissue type Plasminogen Activator (t-PA).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed