BDBM50104360 4-[2,5-Bis-(4-fluoro-phenyl)-3H-imidazol-4-yl]-pyridine::CHEMBL316264

SMILES Fc1ccc(cc1)-c1nc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1

InChI Key InChIKey=UPYHVTCMTMZKAX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50104360   

TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104360(4-[2,5-Bis-(4-fluoro-phenyl)-3H-imidazol-4-yl]-pyr...)
Affinity DataIC50:  2.00E+3nMAssay Description:Binding affinity towards human glucagon receptor in absence of Mg2+ expressed as IC50More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104360(4-[2,5-Bis-(4-fluoro-phenyl)-3H-imidazol-4-yl]-pyr...)
Affinity DataIC50:  100nMAssay Description:Binding affinity towards human Mitogen-activated protein kinase p38 expressed as IC50More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104360(4-[2,5-Bis-(4-fluoro-phenyl)-3H-imidazol-4-yl]-pyr...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human glucagon receptor expressed in CHO cell membranes by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails Article