BDBM50104375 4-[2-(4-Chloro-phenyl)-5-(2-phenoxy-phenyl)-3H-imidazol-4-yl]-pyridine::CHEMBL314701

SMILES Clc1ccc(cc1)-c1nc(c([nH]1)-c1ccccc1Oc1ccccc1)-c1ccncc1

InChI Key InChIKey=COXXCKLSWHHFDS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50104375   

TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104375(4-[2-(4-Chloro-phenyl)-5-(2-phenoxy-phenyl)-3H-imi...)
Affinity DataIC50:  6.5nMAssay Description:Binding affinity towards human glucagon receptor in absence of Mg2+ expressed as IC50More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104375(4-[2-(4-Chloro-phenyl)-5-(2-phenoxy-phenyl)-3H-imi...)
Affinity DataIC50:  150nMAssay Description:Binding affinity towards human Mitogen-activated protein kinase p38 expressed as IC50More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104375(4-[2-(4-Chloro-phenyl)-5-(2-phenoxy-phenyl)-3H-imi...)
Affinity DataIC50:  6.5nMAssay Description:Binding affinity towards human glucagon receptor in absence of Mg2+ expressed as IC50More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104375(4-[2-(4-Chloro-phenyl)-5-(2-phenoxy-phenyl)-3H-imi...)
Affinity DataIC50:  150nMAssay Description:Inhibition of human glucagon receptor expressed in CHO cell membranes by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails Article