BDBM50104563 2-{2-(3,5-Dimethyl-phenyl)-3-[(S)-1-methyl-2-(4-pyridin-4-yl-butylamino)-ethyl]-1H-indol-5-yl}-1-(dodecahydro-carbazol-9-yl)-2-methyl-propan-1-one::CHEMBL313004

SMILES C[C@H](CNCCCCc1ccncc1)c1c([nH]c2ccc(cc12)C(C)(C)C(=O)N1C2CCCCC2C2CCCCC12)-c1cc(C)cc(C)c1

InChI Key InChIKey=BKSRWLOPOUNWJY-AMMNUJJISA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50104563   

TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104563(2-{2-(3,5-Dimethyl-phenyl)-3-[(S)-1-methyl-2-(4-py...)
Affinity DataIC50:  21nMAssay Description:Binding inhibition towards human pituitary gonadotropin-releasing hormone receptor using [125I]-buserelin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104563(2-{2-(3,5-Dimethyl-phenyl)-3-[(S)-1-methyl-2-(4-py...)
Affinity DataIC50:  31nMAssay Description:In vitro functional antagonism via inhibition of GnRH-stimulated phosphatidylinositol (PI) hydrolysis in cloned Chinese hamster ovary (CHO) cells sta...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed