BDBM50104653 CHEMBL88308::[1,4]Thiazepan-(5E)-ylideneamine::[1,4]Thiazepan-(5Z)-ylideneamine

SMILES NC1=NCCSCC1

InChI Key InChIKey=VXILVSMPTBRDEC-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50104653   

TargetNitric oxide synthase, brain(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50104653(CHEMBL88308 | [1,4]Thiazepan-(5E)-ylideneamine | [...)
Affinity DataIC50:  6.80E+3nMAssay Description:Inhibition of Neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50104653(CHEMBL88308 | [1,4]Thiazepan-(5E)-ylideneamine | [...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50104653(CHEMBL88308 | [1,4]Thiazepan-(5E)-ylideneamine | [...)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibitory concentration against Neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50104653(CHEMBL88308 | [1,4]Thiazepan-(5E)-ylideneamine | [...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibitory concentration against Inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104653(CHEMBL88308 | [1,4]Thiazepan-(5E)-ylideneamine | [...)
Affinity DataIC50:  1.34E+4nMAssay Description:Inhibitory concentration against Endothelial nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104653(CHEMBL88308 | [1,4]Thiazepan-(5E)-ylideneamine | [...)
Affinity DataIC50:  4.36E+4nMAssay Description:Inhibition of endothelial nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed