BDBM50104848 CHEMBL112903::N-[3-(3-Ethyl-4-fluoro-phenyl)-2,2-dimethyl-cyclopropanecarbonyl]-guanidine

SMILES CCc1cc(ccc1F)[C@@H]1[C@@H](C(=O)NC(N)=N)C1(C)C

InChI Key InChIKey=QQDGVOCPOVILRK-NEPJUHHUSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50104848   

TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104848(CHEMBL112903 | N-[3-(3-Ethyl-4-fluoro-phenyl)-2,2-...)
Affinity DataIC50:  5nMAssay Description:Screened in AP1 cells expressing human NHE-1 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed