BDBM50105072 8-(6-Chloro-benzo[1,3]dioxol-5-ylmethyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL115652
SMILES Clc1cc2OCOc2cc1CN1CCC2(CC1)N(CNC2=O)c1ccccc1
InChI Key InChIKey=QATNQFJQXRFOHL-UHFFFAOYSA-N
Data 10 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50105072
Affinity DataIC50: 138nMAssay Description:Inhibition of ligand binding to human delta opioid receptor.More data for this Ligand-Target Pair
Affinity DataIC50: 138nMAssay Description:Binding affinity against delta-opiate receptor (human) using [3H]-DPDPE radioligandMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1F/alpha-1S(Homo sapiens (Human))
Universities Of Lille
Curated by ChEMBL
Universities Of Lille
Curated by ChEMBL
Affinity DataIC50: 1.11E+3nMAssay Description:Binding affinity against L-type calcium channel verapamil siteMore data for this Ligand-Target Pair
Affinity DataIC50: 5.70nMAssay Description:Binding affinity against opioid receptor kappa 1 using [3H]- U-69,593 radioligandMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Universities Of Lille
Curated by ChEMBL
Universities Of Lille
Curated by ChEMBL
Affinity DataIC50: 581nMAssay Description:Inhibition of sigma receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 97nMAssay Description:Inhibition of human ORL1 orphanin receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Binding affinity against mu opiate receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 2.12E+3nMAssay Description:Inhibition of human dopamine receptor D3More data for this Ligand-Target Pair
Affinity DataIC50: 5.70nMAssay Description:Binding affinity against opioid receptor kappa 1 by using [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Binding affinity against mu-opiate receptor (human) using [3H]DAMGO radioligandMore data for this Ligand-Target Pair