BDBM50105145 4-[4-(1,1-Difluoro-2-hydroxy-ethyl)-phenoxy]-thieno[2,3-c]pyridine-2-carboxylic acid methylamide::CHEMBL324824

SMILES CNC(=O)c1cc2c(Oc3ccc(cc3)C(F)(F)CO)cncc2s1

InChI Key InChIKey=GIXDQSVCWHRYGO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50105145   

TargetVascular cell adhesion protein 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105145(4-[4-(1,1-Difluoro-2-hydroxy-ethyl)-phenoxy]-thien...)
Affinity DataIC50:  470nMAssay Description:Inhibition of VCAM-1 in human endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntercellular adhesion molecule 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105145(4-[4-(1,1-Difluoro-2-hydroxy-ethyl)-phenoxy]-thien...)
Affinity DataIC50:  320nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM1) in human endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE-selectin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105145(4-[4-(1,1-Difluoro-2-hydroxy-ethyl)-phenoxy]-thien...)
Affinity DataIC50:  300nMAssay Description:Inhibition of selectin E in human endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed