BDBM50105159 4-(4-Chloro-phenoxy)-thieno[2,3-c]pyridine-2-carboxylic acid methylamide::CHEMBL118074
SMILES CNC(=O)c1cc2c(Oc3ccc(Cl)cc3)cncc2s1
InChI Key InChIKey=CMEFLKIFRPLMJK-UHFFFAOYSA-N
Data 11 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50105159
Affinity DataIC50: 200nMAssay Description:In vitro inhibitory potency compared to PMA induced VCAM-1 expression in human endothelial cells (ELISA assay)More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM1) in human endothelial cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:In vitro inhibitory potency compared to IL-1beta induced Intercellular adhesion molecule-1 in human endothelial cells (ELISA assay)More data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:In vitro inhibitory potency compared to IL-1beta induced VCAM-1 expression in human endothelial cells (ELISA assay)More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:In vitro inhibitory potency compared to PMA induced Intercellular adhesion molecule-1 expression in human endothelial cells (ELISA assay)More data for this Ligand-Target Pair
Affinity DataIC50: 8.20nMAssay Description:Inhibition of full length human recombinant His-tagged CDK8/Cyclin C expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:In vitro inhibitory potency compared to TNF-alpha induced Selectin E expression in human endothelial cells (ELISA assay)More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:In vitro inhibitory potency compared to TNF-alpha induced Intercellular adhesion molecule-1 in human endothelial cells (ELISA assay)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of VCAM-1 in human endothelial cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of selectin E in human endothelial cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:In vitro inhibitory potency compared to IL-1beta induced Selectin E in human endothelial cells (ELISA assay)More data for this Ligand-Target Pair