BDBM50105685 (E)-3-[4-(Benzenesulfonyl-methyl-amino)-phenyl]-N-hydroxy-acrylamide::3-[4-(Benzenesulfonyl-methyl-amino)-phenyl]-N-hydroxy-acrylamide::CHEMBL97387::N-hydroxy-3-(4-(N-methylphenylsulfonamido)phenyl)acrylamide::US8796330, 170

SMILES CN(c1ccc(\C=C\C(=O)NO)cc1)S(=O)(=O)c1ccccc1

InChI Key InChIKey=IAMCGWXEUBEXCF-FMIVXFBMSA-N

Data  4 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50105685   

TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

US Patent
LigandPNGBDBM50105685((E)-3-[4-(Benzenesulfonyl-methyl-amino)-phenyl]-N-...)
Affinity DataIC50:  570nMT: 2°CAssay Description:For deacetylase assays, 20,000 cpm of the [3H]-metabolically labeled acetylated histone substrate (M. Yoshida et al., J. Biol. Chem. 265(28): 17174-1...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

US Patent
LigandPNGBDBM50105685((E)-3-[4-(Benzenesulfonyl-methyl-amino)-phenyl]-N-...)
Affinity DataIC50:  600nMAssay Description:In vitro inhibition of partially purified recombinant human Histone deacetylase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

US Patent
LigandPNGBDBM50105685((E)-3-[4-(Benzenesulfonyl-methyl-amino)-phenyl]-N-...)
Affinity DataEC50: >2.50E+4nMAssay Description:Concentration of compound required for acetylation of histone-4 in human T24 cancer cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed