BDBM50106243 2-(2-Hydroxy-biphenyl-3-yl)-6-methyl-1H-indole-5-carboxamidine::CHEMBL127278

SMILES Cc1cc2[nH]c(cc2cc1C(N)=N)-c1cccc(-c2ccccc2)c1O

InChI Key InChIKey=QRPASZARTYLGAR-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50106243   

TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50106243(2-(2-Hydroxy-biphenyl-3-yl)-6-methyl-1H-indole-5-c...)
Affinity DataKi:  100nMAssay Description:The compound was tested for inhibition of human urokinase type plasminogen activator (microPa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50106243(2-(2-Hydroxy-biphenyl-3-yl)-6-methyl-1H-indole-5-c...)
Affinity DataKi:  210nMAssay Description:The compound was tested for inhibition of human plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1/Trypsin-2(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50106243(2-(2-Hydroxy-biphenyl-3-yl)-6-methyl-1H-indole-5-c...)
Affinity DataKi:  1.60E+3nMAssay Description:The compound was tested for inhibition of human trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50106243(2-(2-Hydroxy-biphenyl-3-yl)-6-methyl-1H-indole-5-c...)
Affinity DataKi:  7.00E+3nMAssay Description:The compound was tested for inhibition of human coagulation factor VIIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50106243(2-(2-Hydroxy-biphenyl-3-yl)-6-methyl-1H-indole-5-c...)
Affinity DataKi:  3.90E+4nMAssay Description:The compound was tested for inhibition of human tissue plasminogen activatorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50106243(2-(2-Hydroxy-biphenyl-3-yl)-6-methyl-1H-indole-5-c...)
Affinity DataKi: >7.50E+4nMAssay Description:Binding affinity against human coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50106243(2-(2-Hydroxy-biphenyl-3-yl)-6-methyl-1H-indole-5-c...)
Affinity DataKi: >7.50E+4nMAssay Description:The compound was tested for inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed