BDBM50106899 CHEMBL105600::N-[(E)-(R)-3-(1-Carbamoyl-cyclohexylcarbamoyl)-1-(4-chloro-benzyl)-allyl]-N-methyl-3,5-bis-trifluoromethyl-benzamide

SMILES CN([C@H](Cc1ccc(Cl)cc1)\C=C\C(=O)NC1(CCCCC1)C(N)=O)C(=O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=LFHWHZNDQKZPOH-CZQLGGELSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50106899   

TargetSubstance-K receptor(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50106899(CHEMBL105600 | N-[(E)-(R)-3-(1-Carbamoyl-cyclohexy...)
Affinity DataIC50:  66nMAssay Description:In vitro binding affinity for Tachykinin receptor 2 of human-CHO cells using 125 I-NKA radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50106899(CHEMBL105600 | N-[(E)-(R)-3-(1-Carbamoyl-cyclohexy...)
Affinity DataIC50:  1nMAssay Description:In vitro binding affinity for Tachykinin receptor 1 of bovine retinal membranes using [3H]-Sar9-substance P as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed