BDBM50107124 2,9-Dimethoxy-11,12-dihydro-dibenzo[c,g][1,2]diazocine 5,6-dioxide::CHEMBL344184

SMILES COc1ccc2N([O-])[N+](=O)c3ccc(OC)cc3CCc2c1

InChI Key InChIKey=PSEWIQFVVLQNNL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50107124   

TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50107124(2,9-Dimethoxy-11,12-dihydro-dibenzo[c,g][1,2]diazo...)
Affinity DataIC50:  1.04E+4nMAssay Description:In vitro inhibitory activity against Bak-Bh3 peptide binding to the Bcl-2 using human myeloid leukemia cell line HL-60More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50107124(2,9-Dimethoxy-11,12-dihydro-dibenzo[c,g][1,2]diazo...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibitory activity against Bcl-2 using bromide assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed