BDBM50107595 (S)-1-(2-Amino-2-carboxyethyl)-6,7-dihydro-1H-cyclopenta[d]-pyrimidin-2,4(1H,3H)dione::(S)-2-AMINO-3-(1,3,5,7-PENTAHYDRO-2,4-DIOXO-CYCLOPENTA[E]PYRIMIDIN-1-YL) PROIONIC ACID::2-Amino-3-(2,4-dioxo-2,3,4,5,6,7-hexahydro-cyclopentapyrimidin-1-yl)-propionic acid::CHEMBL337577
SMILES N[C@@H](Cn1c2CCCc2c(=O)[nH]c1=O)C(O)=O
InChI Key InChIKey=VSGUEKZRMJVQOH-LURJTMIESA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 26 hits for monomerid = 50107595
TargetGlutamate receptor ionotropic, kainate 1(RAT)
European Research Centre For Drug Discovery And Development (Natsyndrugs)
Curated by ChEMBL
European Research Centre For Drug Discovery And Development (Natsyndrugs)
Curated by ChEMBL
Affinity DataKi: 44nMAssay Description:Displacement of [3H]SYM2081 from rat recombinant iGluR5(Q)1b expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, kainate 1(RAT)
European Research Centre For Drug Discovery And Development (Natsyndrugs)
Curated by ChEMBL
European Research Centre For Drug Discovery And Development (Natsyndrugs)
Curated by ChEMBL
Affinity DataKi: 44nMAssay Description:Displacement of [3H]SYM2081 from recombinant homomeric rat GluK1 receptor expressed in baculovirus infected Sf9 insect cell membranesMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, kainate 1(RAT)
European Research Centre For Drug Discovery And Development (Natsyndrugs)
Curated by ChEMBL
European Research Centre For Drug Discovery And Development (Natsyndrugs)
Curated by ChEMBL
Affinity DataKi: 44nMAssay Description:Displacement of [3H]SYM2081 from rat GluK1 expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetGlutamate receptor 1(Rattus norvegicus (Rat))
European Research Centre For Drug Discovery And Development (Natsyndrugs)
Curated by ChEMBL
European Research Centre For Drug Discovery And Development (Natsyndrugs)
Curated by ChEMBL
Affinity DataKi: 109nMAssay Description:Displacement of (R,S)-[5-methyl-3H]AMPA from rat recombinant flop iGluR1 expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 109nMAssay Description:Binding affinity towards GluR1 receptor from rat brainMore data for this Ligand-Target Pair
Affinity DataKi: 218nMAssay Description:Binding affinity towards Ionotropic glutamate receptor AMPA 2 from rat brainMore data for this Ligand-Target Pair
Affinity DataKi: 223nMAssay Description:Displacement of [3H]AMPA from recombinant homomeric rat GluA2 receptor expressed in baculovirus infected Sf9 insect cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 223nMAssay Description:Displacement of (R,S)-[5-methyl-3H]AMPA from rat recombinant flop iGluR2(R) expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 223nMAssay Description:Displacement of [3H]AMPA from rat GluA2 expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.76E+3nMAssay Description:Binding affinity towards GluR4 receptor from rat brainMore data for this Ligand-Target Pair
TargetGlutamate receptor 3(RAT)
European Research Centre For Drug Discovery And Development (Natsyndrugs)
Curated by ChEMBL
European Research Centre For Drug Discovery And Development (Natsyndrugs)
Curated by ChEMBL
Affinity DataKi: 1.89E+3nMAssay Description:Displacement of (R,S)-[5-methyl-3H]AMPA from rat recombinant flop iGluR3 expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.09E+3nMAssay Description:Displacement of (R,S)-[5-methyl-3H]AMPA from rat recombinant flop iGluR4 expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetGlutamate receptor 3(RAT)
European Research Centre For Drug Discovery And Development (Natsyndrugs)
Curated by ChEMBL
European Research Centre For Drug Discovery And Development (Natsyndrugs)
Curated by ChEMBL
Affinity DataKi: 2.14E+3nMAssay Description:Binding affinity towards Ionotropic glutamate receptor AMPA 3 from rat brainMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, kainate 3(Rattus norvegicus)
University of Siena
Curated by ChEMBL
University of Siena
Curated by ChEMBL
Affinity DataKi: 5.09E+3nMAssay Description:Displacement of [3H]SYM2081 from recombinant homomeric rat GluK3 receptor expressed in baculovirus infected Sf9 insect cell membranesMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, kainate 3(Rattus norvegicus)
University of Siena
Curated by ChEMBL
University of Siena
Curated by ChEMBL
Affinity DataKi: 5.09E+3nMAssay Description:Displacement of [3H]SYM2081 from rat GluK3 expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, kainate 2(Rattus norvegicus)
University of Siena
Curated by ChEMBL
University of Siena
Curated by ChEMBL
Affinity DataKi: >1.00E+6nMAssay Description:Displacement of [3H]SYM2081 from recombinant homomeric rat GluK2 receptor expressed in baculovirus infected Sf9 insect cell membranesMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, kainate 2(Rattus norvegicus)
University of Siena
Curated by ChEMBL
University of Siena
Curated by ChEMBL
Affinity DataKi: >1.00E+6nMAssay Description:Displacement of [3H]SYM2081 from rat GluK2 expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, kainate 2(Rattus norvegicus)
University of Siena
Curated by ChEMBL
University of Siena
Curated by ChEMBL
Affinity DataKi: >1.00E+6nMAssay Description:Displacement of [3H]kainic acid from rat recombinant iGluR6(V,C,R) receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetGlutamate receptor 3(RAT)
European Research Centre For Drug Discovery And Development (Natsyndrugs)
Curated by ChEMBL
European Research Centre For Drug Discovery And Development (Natsyndrugs)
Curated by ChEMBL
Affinity DataEC50: 2.24E+5nMAssay Description:The potency at recombinant rat AMPA-R was measured on Ionotropic glutamate receptor AMPA 3 expressed in Xenopus Laevis oocytesMore data for this Ligand-Target Pair
Affinity DataEC50: 3.43E+4nMAssay Description:Agonist activity at cyclothiazide-desensitized rat recombinant flop iGluR4c expressed in Xenopus laevis oocytes by two electrode voltage-clamp electr...More data for this Ligand-Target Pair
TargetGlutamate receptor 3(RAT)
European Research Centre For Drug Discovery And Development (Natsyndrugs)
Curated by ChEMBL
European Research Centre For Drug Discovery And Development (Natsyndrugs)
Curated by ChEMBL
Affinity DataEC50: 2.24E+5nMAssay Description:Agonist activity at cyclothiazide-desensitized rat recombinant flop iGluR3 expressed in Xenopus laevis oocytes by two electrode voltage-clamp electro...More data for this Ligand-Target Pair
Affinity DataEC50: 1.39E+4nMAssay Description:Agonist activity at cyclothiazide-desensitized rat recombinant flop iGluR2(Q) expressed in Xenopus laevis oocytes by two electrode voltage-clamp elec...More data for this Ligand-Target Pair
TargetGlutamate receptor 1(Rattus norvegicus (Rat))
European Research Centre For Drug Discovery And Development (Natsyndrugs)
Curated by ChEMBL
European Research Centre For Drug Discovery And Development (Natsyndrugs)
Curated by ChEMBL
Affinity DataEC50: 2.49E+4nMAssay Description:Agonist activity at cyclothiazide-desensitized rat recombinant flop iGluR1 expressed in Xenopus laevis oocytes by two electrode voltage-clamp electro...More data for this Ligand-Target Pair
Affinity DataEC50: 1.39E+4nMAssay Description:The potency at recombinant rat AMPA-R was measured on receptor Ionotropic glutamate receptor AMPA 2 expressed in Xenopus Laevis oocytesMore data for this Ligand-Target Pair
Affinity DataEC50: 3.43E+4nMAssay Description:The potency at recombinant rat AMPA-R was measured on GluR4 receptor expressed in Xenopus Laevis oocytesMore data for this Ligand-Target Pair
Affinity DataEC50: 2.49E+4nMAssay Description:The potency at recombinant rat AMPA-R was measured on GluR1 receptor expressed in Xenopus Laevis oocytesMore data for this Ligand-Target Pair