BDBM50107622 CHEMBL342145::N-Cyanomethyl-2-diphenylacetylamino-3-phenyl-propionamide

SMILES O=C(NCC#N)[C@H](Cc1ccccc1)NC(=O)C(c1ccccc1)c1ccccc1

InChI Key InChIKey=RAWKSIKXMYXSHO-QFIPXVFZSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50107622   

TargetCathepsin B(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107622(CHEMBL342145 | N-Cyanomethyl-2-diphenylacetylamino...)
Affinity DataIC50:  496nMAssay Description:Inhibitiory activity against recombinant human cathepsin B (cat B) expressed in baculovirus.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107622(CHEMBL342145 | N-Cyanomethyl-2-diphenylacetylamino...)
Affinity DataIC50:  496nMAssay Description:Inhibition of recombinant human cathepsin B expressed in baculovirus expression system using Z-Arg-Arg-AMC as substrate incubated for 20 mins by fluo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107622(CHEMBL342145 | N-Cyanomethyl-2-diphenylacetylamino...)
Affinity DataIC50:  31nMAssay Description:Inhibitiory activity of the compound against recombinant human cathepsin L (cat L) expressed in baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107622(CHEMBL342145 | N-Cyanomethyl-2-diphenylacetylamino...)
Affinity DataIC50:  48nMAssay Description:Inhibitiory activity of the compound against recombinant human cathepsin S (cat S) expressed in baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed