BDBM50107800 CHEMBL356126::{2-[(4'-Chloro-6-methyl-biphenyl-2-carbonyl)-amino]-6,7,8,9-tetrahydro-5H-benzocyclohepten-7-yl}-carbamic acid methyl ester

SMILES COC(=O)NC1CCc2ccc(NC(=O)c3cccc(C)c3-c3ccc(Cl)cc3)cc2CC1

InChI Key InChIKey=OLXBRQXHOJCVJV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50107800   

TargetApolipoprotein B-100(Homo sapiens (Human))
Novartis Institute For Biomedical Reasearch

Curated by ChEMBL
LigandPNGBDBM50107800(CHEMBL356126 | {2-[(4'-Chloro-6-methyl-biphenyl-2-...)
Affinity DataIC50:  2nMAssay Description:Inhibition of apolipoprotein B (apoB) secreted by human hepatoma cells (Hep G2) at 100 nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Novartis Institute For Biomedical Reasearch

Curated by ChEMBL
LigandPNGBDBM50107800(CHEMBL356126 | {2-[(4'-Chloro-6-methyl-biphenyl-2-...)
Affinity DataIC50:  80nMAssay Description:In vitro inhibitory activity against MTP using MTP transfer assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed