BDBM50108777 6,7-Dihydro-1H,5H-pyrrolo[2,3-c]azepine-4,8-dione::CHEMBL357047::aldisin

SMILES O=C1CCNC(=O)c2[nH]ccc12

InChI Key InChIKey=AAPGLCCSVSGLFH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50108777   

TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50108777(6,7-Dihydro-1H,5H-pyrrolo[2,3-c]azepine-4,8-dione ...)
Affinity DataIC50: >2.50E+3nMAssay Description:Inhibition of Mitogen-activated protein kinase (MAPK)phosphorylation by activated MEK-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50108777(6,7-Dihydro-1H,5H-pyrrolo[2,3-c]azepine-4,8-dione ...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of MEK1 phosphorylation by activated human recombinant RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed