BDBM50108847 CHEMBL162474::benzyl (S)-4-methyl-1-oxo-1-((S)-3-oxo-1-phenyl-4-(3-phenylpropylthio)butan-2-ylamino)pentan-2-ylcarbamate::{1-[1-Benzyl-2-oxo-3-(3-phenyl-propylsulfanyl)-propylcarbamoyl]-3-methyl-butyl}-carbamic acid benzyl ester

SMILES CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)CSCCCc1ccccc1

InChI Key InChIKey=BVJMYPXCAYDMBJ-KYJUHHDHSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50108847   

TargetCruzipain(Trypanosoma cruzi)
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50108847(CHEMBL162474 | benzyl (S)-4-methyl-1-oxo-1-((S)-3-...)
Affinity DataKi:  1nMAssay Description:Inhibition of Trypanosoma cruzi cruzainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50108847(CHEMBL162474 | benzyl (S)-4-methyl-1-oxo-1-((S)-3-...)
Affinity DataKi:  1nMAssay Description:Inhibitory activity against cruzain, the major cysteine protease found in T. cruziMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50108847(CHEMBL162474 | benzyl (S)-4-methyl-1-oxo-1-((S)-3-...)
Affinity DataKi:  4.70nMAssay Description:Inhibitory activity of the compound against human Cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50108847(CHEMBL162474 | benzyl (S)-4-methyl-1-oxo-1-((S)-3-...)
Affinity DataKi:  136nMAssay Description:Inhibitory activity of the compound against human Cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed