BDBM50108855 CHEMBL352168::[1-(3-tert-Butylsulfanyl-2-oxo-1-phenethyl-propylcarbamoyl)-3-methyl-butyl]-carbamic acid pyridin-3-ylmethyl ester

SMILES CC(C)C[C@H](NC(=O)OCc1cccnc1)C(=O)N[C@@H](CCc1ccccc1)C(=O)CSC(C)(C)C

InChI Key InChIKey=WUKLOIZMYLWBNL-ZEQRLZLVSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50108855   

TargetCruzipain(Trypanosoma cruzi)
University Of California

Curated by ChEMBL
LigandPNGBDBM50108855(CHEMBL352168 | [1-(3-tert-Butylsulfanyl-2-oxo-1-ph...)
Affinity DataKi:  2nMAssay Description:Inhibitory activity against cruzain, the major cysteine protease found in T. cruziMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50108855(CHEMBL352168 | [1-(3-tert-Butylsulfanyl-2-oxo-1-ph...)
Affinity DataKi:  44nMAssay Description:Inhibitory activity of the compound against human Cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50108855(CHEMBL352168 | [1-(3-tert-Butylsulfanyl-2-oxo-1-ph...)
Affinity DataKi:  1.30E+3nMAssay Description:Inhibitory activity of the compound against human Cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed