BDBM50109154 CHEMBL3601540

SMILES NS(=O)(=O)Oc1ccc(NC(=O)N2CCN(CC2)c2nccc(n2)-c2cc3ccccc3o2)cc1

InChI Key InChIKey=HAPSXOFHRWGPLA-UHFFFAOYSA-N

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50109154   

TargetCarbonic anhydrase 12(Homo sapiens (Human))
University Of Cagliari

Curated by ChEMBL
LigandPNGBDBM50109154(CHEMBL3601540)
Affinity DataKi:  1nMAssay Description:Inhibition of human recombinant carbonic anhydrase-12 pre-incubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Cagliari

Curated by ChEMBL
LigandPNGBDBM50109154(CHEMBL3601540)
Affinity DataKi:  1nMAssay Description:Inhibition of human recombinant carbonic anhydrase-2 pre-incubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
University Of Cagliari

Curated by ChEMBL
LigandPNGBDBM50109154(CHEMBL3601540)
Affinity DataKi:  6.70nMAssay Description:Inhibition of human recombinant carbonic anhydrase-9 pre-incubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
University Of Cagliari

Curated by ChEMBL
LigandPNGBDBM50109154(CHEMBL3601540)
Affinity DataKi:  70nMAssay Description:Inhibition of human recombinant carbonic anhydrase-1 pre-incubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
University Of Cagliari

Curated by ChEMBL
LigandPNGBDBM50109154(CHEMBL3601540)
Affinity DataIC50:  139nMAssay Description:Inhibition of steroid sulfatase in human JEG3 cell using [3H] E1S as substrate after 1 hr by scintillation spectrometry analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed