BDBM50109270 CHEMBL3601535

SMILES Cc1cccc(N2CCN(CC2)C(=O)Nc2ccc(OS(N)(=O)=O)cc2)c1C

InChI Key InChIKey=LIXCKEGDQZELHR-UHFFFAOYSA-N

Data  5 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50109270   

TargetCarbonic anhydrase 12(Homo sapiens (Human))
University Of Cagliari

Curated by ChEMBL
LigandPNGBDBM50109270(CHEMBL3601535)
Affinity DataKi:  1nMAssay Description:Inhibition of human recombinant carbonic anhydrase-12 pre-incubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Cagliari

Curated by ChEMBL
LigandPNGBDBM50109270(CHEMBL3601535)
Affinity DataKi:  11nMAssay Description:Inhibition of human recombinant carbonic anhydrase-2 pre-incubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
University Of Cagliari

Curated by ChEMBL
LigandPNGBDBM50109270(CHEMBL3601535)
Affinity DataKi:  32nMAssay Description:Inhibition of human recombinant carbonic anhydrase-9 pre-incubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
University Of Cagliari

Curated by ChEMBL
LigandPNGBDBM50109270(CHEMBL3601535)
Affinity DataKi:  64nMAssay Description:Inhibition of human recombinant carbonic anhydrase-1 pre-incubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Cagliari

Curated by ChEMBL
LigandPNGBDBM50109270(CHEMBL3601535)
Affinity DataKi:  1.09E+6nMAssay Description:Inhibition of recombinant human carbonic anhydrase 4 incubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red-based stopped-f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
University Of Cagliari

Curated by ChEMBL
LigandPNGBDBM50109270(CHEMBL3601535)
Affinity DataIC50:  66nMAssay Description:Inhibition of steroid sulfatase in human JEG3 cell using [3H] E1S as substrate after 1 hr by scintillation spectrometry analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed