BDBM50109529 CHEMBL3601242

SMILES Cn1cc(Nc2ncc(Cl)c(NCc3cccc(NC(=O)C=C)c3)n2)cn1

InChI Key InChIKey=UITZSWYAMHHKPO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50109529   

TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50109529(CHEMBL3601242)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of JAK3 (unknown origin) by Z'-Lyte assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50109529(CHEMBL3601242)
Affinity DataIC50:  180nMAssay Description:Inhibition of TTK (unknown origin) by LanthaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50109529(CHEMBL3601242)
Affinity DataIC50:  49nMAssay Description:Inhibition of JAK1 (unknown origin) by Z'-Lyte assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50109529(CHEMBL3601242)
Affinity DataIC50:  107nMAssay Description:Inhibition of JAK2 (unknown origin) by Z'-Lyte assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed