BDBM50109652 2-Amino-3-[3-hydroxy-4-(3-hydroxy-phenyl)-isoxazol-5-yl]-propionic acid::CHEMBL368556

SMILES N[C@@H](Cc1o[nH]c(=O)c1-c1cccc(O)c1)C(O)=O

InChI Key InChIKey=GQMGXQFOFZCRPO-QMMMGPOBSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50109652   

TargetMetabotropic glutamate receptor 1(RAT)
The Royal Danish School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50109652(2-Amino-3-[3-hydroxy-4-(3-hydroxy-phenyl)-isoxazol...)
Affinity DataKi:  2.26E+5nMAssay Description:The compound was tested for the receptor binding affinity at Metabotropic glutamate receptor 1 using established second messenger assay systems.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
The Royal Danish School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50109652(2-Amino-3-[3-hydroxy-4-(3-hydroxy-phenyl)-isoxazol...)
Affinity DataKi: >1.00E+6nMAssay Description:The compound was tested for the receptor binding affinity at Metabotropic glutamate receptor 2 using established second messenger assay systems.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
The Royal Danish School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50109652(2-Amino-3-[3-hydroxy-4-(3-hydroxy-phenyl)-isoxazol...)
Affinity DataKi: >1.00E+6nMAssay Description:The compound was tested for the receptor binding affinity at Metabotropic glutamate receptor 4 using established second messenger assay systems.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(RAT)
The Royal Danish School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50109652(2-Amino-3-[3-hydroxy-4-(3-hydroxy-phenyl)-isoxazol...)
Affinity DataIC50: >1.00E+5nMAssay Description:Concentration of the compound which causes 50% reduction in receptor binding affinity against Ionotropic glutamate receptor ionotropic kainate using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed