BDBM50109656 2-Amino-3-(3-hydroxy-4-naphthalen-2-yl-isoxazol-5-yl)-propionic acid::CHEMBL178058

SMILES N[C@@H](Cc1o[nH]c(=O)c1-c1ccc2ccccc2c1)C(O)=O

InChI Key InChIKey=WSJVPOMJYXGEDF-LBPRGKRZSA-N

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50109656   

TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
The Royal Danish School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50109656(2-Amino-3-(3-hydroxy-4-naphthalen-2-yl-isoxazol-5-...)
Affinity DataKi:  5.30E+4nMAssay Description:The compound was tested for the receptor binding affinity at Metabotropic glutamate receptor 5 using established second messenger assay systems.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(RAT)
The Royal Danish School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50109656(2-Amino-3-(3-hydroxy-4-naphthalen-2-yl-isoxazol-5-...)
Affinity DataKi:  2.49E+5nMAssay Description:The compound was tested for the receptor binding affinity at Metabotropic glutamate receptor 1 using established second messenger assay systems.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
The Royal Danish School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50109656(2-Amino-3-(3-hydroxy-4-naphthalen-2-yl-isoxazol-5-...)
Affinity DataKi: >1.00E+6nMAssay Description:The compound was tested for the receptor binding affinity at Metabotropic glutamate receptor 2 using established second messenger assay systems.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
The Royal Danish School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50109656(2-Amino-3-(3-hydroxy-4-naphthalen-2-yl-isoxazol-5-...)
Affinity DataKi: >1.00E+6nMAssay Description:The compound was tested for the receptor binding affinity at Metabotropic glutamate receptor 4 using established second messenger assay systems.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(RAT)
The Royal Danish School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50109656(2-Amino-3-(3-hydroxy-4-naphthalen-2-yl-isoxazol-5-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Concentration of the compound which causes 50% reduction in receptor binding affinity against Ionotropic glutamate receptor ionotropic kainate using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed