BDBM50109761 2,2-Dimethyl-propionic acid (S)-2-{2-[((S)-1-{(S)-2-[2-(4-carboxymethoxy-phenoxy)-acetylamino]-3-methyl-butyryl}-pyrrolidine-2-carbonyl)-amino]-3-methyl-butyryl}-benzooxazol-4-yl ester::CHEMBL358943

SMILES CC(C)[C@H](NC(=O)COc1ccc(OCC(O)=O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)c1nc2c(OC(=O)C(C)(C)C)cccc2o1

InChI Key InChIKey=WOYYPGZEYALERU-YDZBWFOPSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50109761   

TargetNeutrophil elastase(Homo sapiens (Human))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50109761(2,2-Dimethyl-propionic acid (S)-2-{2-[((S)-1-{(S)-...)
Affinity DataIC50:  8.90nMAssay Description:In vitro inhibition of the human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate Suc-Ala-Pro-Ala-MCAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed