BDBM50109821 CHEBI:87103::CHEMBL21156::US10981896, Compound 420099
SMILES CC(C)(C)c1nc2c([nH]1)c1cc[nH]c(=O)c1c1cc(F)ccc21
InChI Key InChIKey=VNDWQCSOSCCWIP-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50109821
Affinity DataIC50: 15nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human JAK2 (835 to 1132 residues)More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of TYK2 (unknown origin)More data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of IKK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of FynT (unknown origin)More data for this Ligand-Target Pair