BDBM50111476 1-[5-(4''-Chloro-biphenyl-4-yloxy)-pentyl]-3-pyridin-4-yl-imidazolidin-2-one::1-[5-(4'-Chloro-biphenyl-4-yloxy)-pentyl]-3-pyridin-4-yl-imidazolidin-2-one::CHEMBL45426

SMILES Clc1ccc(cc1)-c1ccc(OCCCCCN2CCN(C2=O)c2ccncc2)cc1

InChI Key InChIKey=WXSUPRFKEUWQEL-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50111476   

TargetGenome polyprotein(Human enterovirus 71 (strain BrCr) (Ev 71))
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50111476(1-[5-(4''-Chloro-biphenyl-4-yloxy)-pentyl]-3-pyrid...)
Affinity DataEC50:  91nMAssay Description:Inhibition of Enterovirus 71 Shenzhen/120F1/09 capsid infected in human RD cells assessed as reduction in virus-induced cell death after 72 hrs by CC...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50111476(1-[5-(4''-Chloro-biphenyl-4-yloxy)-pentyl]-3-pyrid...)
Affinity DataIC50:  1.31E+3nMAssay Description:Inhibitory activity against Echovirus 9 using plaque reduction assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed