BDBM50111695 5-Bromo-N-hydroxy-2-[(4-methoxy-benzenesulfonyl)-methyl-amino]-3-methyl-benzamide::5-bromo-N-hydroxy-2-(4-methoxy-N-methylphenylsulfonamido)-3-methylbenzamide::CHEMBL18614

SMILES COc1ccc(cc1)S(=O)(=O)N(C)c1c(C)cc(Br)cc1C(=O)NO

InChI Key InChIKey=JXCARHJPSZBVFH-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50111695   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50111695(5-Bromo-N-hydroxy-2-[(4-methoxy-benzenesulfonyl)-m...)
Affinity DataIC50:  11nMAssay Description:Inhibition of Matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50111695(5-Bromo-N-hydroxy-2-[(4-methoxy-benzenesulfonyl)-m...)
Affinity DataIC50:  11nMAssay Description:Inhibition of Matrix metalloproteinase-9 activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Sus scrofa (pig))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50111695(5-Bromo-N-hydroxy-2-[(4-methoxy-benzenesulfonyl)-m...)
Affinity DataIC50:  32nMAssay Description:Inhibition of porcine Tumor necrosis factor alpha converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50111695(5-Bromo-N-hydroxy-2-[(4-methoxy-benzenesulfonyl)-m...)
Affinity DataIC50:  21nMAssay Description:Inhibition of Matrix metalloproteinase-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50111695(5-Bromo-N-hydroxy-2-[(4-methoxy-benzenesulfonyl)-m...)
Affinity DataIC50:  114nMAssay Description:Inhibition of Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50111695(5-Bromo-N-hydroxy-2-[(4-methoxy-benzenesulfonyl)-m...)
Affinity DataIC50:  114nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50111695(5-Bromo-N-hydroxy-2-[(4-methoxy-benzenesulfonyl)-m...)
Affinity DataIC50:  114nMAssay Description:Inhibition of Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50111695(5-Bromo-N-hydroxy-2-[(4-methoxy-benzenesulfonyl)-m...)
Affinity DataIC50:  21nMAssay Description:Inhibition of Matrix metalloproteinase-13 activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50111695(5-Bromo-N-hydroxy-2-[(4-methoxy-benzenesulfonyl)-m...)
Affinity DataIC50:  11nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
The M. S. University Of Baroda

Curated by ChEMBL
LigandPNGBDBM50111695(5-Bromo-N-hydroxy-2-[(4-methoxy-benzenesulfonyl)-m...)
Affinity DataIC50:  32nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
The M. S. University Of Baroda

Curated by ChEMBL
LigandPNGBDBM50111695(5-Bromo-N-hydroxy-2-[(4-methoxy-benzenesulfonyl)-m...)
Affinity DataIC50:  32nMAssay Description:Inhibition of Tumor necrosis factor alpha converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed