BDBM50114479 2'-Sulfamoyl-biphenyl-4-carboxylic acid [2-(3-carbamimidoyl-phenoxy)-phenyl]-amide::CHEMBL297835
SMILES NC(=N)c1cccc(Oc2ccccc2NC(=O)c2ccc(cc2)-c2ccccc2S(N)(=O)=O)c1
InChI Key InChIKey=DUVLBBOBLCROSD-UHFFFAOYSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50114479
Affinity DataIC50: 250nMAssay Description:Tested in vitro for the inhibitory activity against kallikreinMore data for this Ligand-Target Pair
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Millennium Pharmaceuticals
Curated by ChEMBL
Millennium Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: >1.81E+5nMAssay Description:Tested in vitro for the inhibitory activity against activated protein C (APC)More data for this Ligand-Target Pair
Affinity DataIC50: >1.10E+4nMAssay Description:Tested in vitro for the inhibitory activity against thrombinMore data for this Ligand-Target Pair
Affinity DataIC50: 3.60nMAssay Description:Inhibitory concentration against coagulation factor Xa.More data for this Ligand-Target Pair
Affinity DataIC50: 4.30E+4nMAssay Description:Tested in vitro for the inhibitory activity against plasminMore data for this Ligand-Target Pair
Affinity DataIC50: 970nMAssay Description:Tested in vitro for the inhibitory activity against trypsinMore data for this Ligand-Target Pair
Affinity DataIC50: 3.60nMAssay Description:Tested in vitro for the inhibitory activity against Coagulation factor XaMore data for this Ligand-Target Pair
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Millennium Pharmaceuticals
Curated by ChEMBL
Millennium Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.80E+4nMAssay Description:Tested in vitro for the inhibitory activity against Tissue plasminogen activator (tissue plasminogen activator)More data for this Ligand-Target Pair