BDBM50114710 CHEMBL329299::N-[2-(2-Cyclohexylmethyl-5-methoxy-benzofuran-3-yl)-ethyl]-acetamide

SMILES COc1ccc2oc(CC3CCCCC3)c(CCNC(C)=O)c2c1

InChI Key InChIKey=MYGLZDVPQSWXNY-UHFFFAOYSA-N

Data  2 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50114710   

TargetMelatonin receptor type 1B(Homo sapiens (Human))
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50114710(CHEMBL329299 | N-[2-(2-Cyclohexylmethyl-5-methoxy-...)
Affinity DataKi:  2.49nMAssay Description:Binding affinity on human melatonin receptor type 1B stably transfected in human embryonic kidney (HEK 293) cells using 2-[125I]-iodomelatonin as rad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50114710(CHEMBL329299 | N-[2-(2-Cyclohexylmethyl-5-methoxy-...)
Affinity DataKi:  66.4nMAssay Description:Binding affinity on human melatonin receptor type 1A stably transfected in human embryonic kidney (HEK 293) using 2-[125I]-iodomelatonin as radioliga...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50114710(CHEMBL329299 | N-[2-(2-Cyclohexylmethyl-5-methoxy-...)
Affinity DataEC50:  481nMAssay Description:Intrinsic activity evaluated on [35S]-GTP -gamma-S binding in Chinese hamster ovarian (CHO) cells, stably expressing human Melatonin receptor type 1AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50114710(CHEMBL329299 | N-[2-(2-Cyclohexylmethyl-5-methoxy-...)
Affinity DataEC50:  10nMAssay Description:Intrinsic activity at human Melatonin receptor type 1B evaluated on [35S]-GTP-gammaS, binding in Chinese hamster ovarian (CHO) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed