BDBM50115777 (E)-1-(4'-Fluorophenyl)-3-(3'',4'',5''-trimethoxyphenyl)prop-2-en-1-one::3-(3-Ethoxy-4,5-dimethoxy-phenyl)-1-(4-fluoro-phenyl)-propenone::CHEMBL59026

SMILES COc1cc(\C=C\C(=O)c2ccc(F)cc2)cc(OC)c1OC

InChI Key InChIKey=WXPAWDMWSJYTRJ-RUDMXATFSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50115777   

TargetGTPase KRas(Homo sapiens (Human))
Wright State University

Curated by ChEMBL
LigandPNGBDBM50115777((E)-1-(4'-Fluorophenyl)-3-(3'',4'',5''-trimethoxyp...)
Affinity DataIC50:  1.59E+4nMAssay Description:Inhibition of GFP-tagged KRAS G12V mutant (unknown origin) expressed in MDCK cells cotransfected with mCherry-CAXX assessed as increase in KRAS G12V-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Universidad De Valencia

Curated by ChEMBL
LigandPNGBDBM50115777((E)-1-(4'-Fluorophenyl)-3-(3'',4'',5''-trimethoxyp...)
Affinity DataIC50:  30nMAssay Description:Inhibitory concentration of the compound required to produce 50% inhibition of the response was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed