BDBM50116210 1-{5-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-thiophen-2-ylmethyl}-piperidin-2-one::CHEMBL420184

SMILES COc1ccccc1N1CCN(Cc2ccc(CN3CCCCC3=O)s2)CC1

InChI Key InChIKey=BTAVBIPIYWDCNO-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50116210   

TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50116210(1-{5-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-t...)
Affinity DataKi:  12nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1D adrenergic receptor expressed in COS cells membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50116210(1-{5-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-t...)
Affinity DataKi:  14nMAssay Description:Displacement of [125I]-HEAT from COS cell membranes expressing human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50116210(1-{5-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-t...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [125I]-HEAT from COS cells membranes expressing human Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed