BDBM50117090(E,E)-Psammaplin A::3-(3-Bromo-4-hydroxy-phenyl)-N-(2-{2-[3-(3-bromo-4-hydroxy-phenyl)-2-hydroxyimino-propionylamino]-ethyldisulfanyl}-ethyl)-2-[(E)-hydroxyimino]-propionamide::3-(3-Bromo-4-hydroxy-phenyl)-N-(2-{2-[3-(3-bromo-4-hydroxy-phenyl)-2-hydroxyimino-propionylamino]-ethyldisulfanyl}-ethyl)-2-hydroxyimino-propionamide::3-(3-Bromo-4-hydroxy-phenyl)-N-[2-(2-{3-(3-bromo-4-hydroxy-phenyl)-2-[(E)-hydroxyimino]-propionylamino}-ethyldisulfanyl)-ethyl]-2-[(E)-hydroxyimino]-propionamide::3-(3-bromo-4-hydroxy-phenyl)-N-[2-(2-{3-(3-bromo-4-hydroxy-phenyl)-2-[hydroxyimino]-propionylamino}-ethyldisulfanyl)-ethyl]-2-[hydroxyimino]-propionamide::CHEMBL83747::Psammaplin A
LigandBDBM50117090((E,E)-Psammaplin A | 3-(3-Bromo-4-hydroxy-phenyl)-...)
Affinity DataIC50: 4.74E+4nMAssay Description:Effective concentration against HIV-1 T215Y strain (AZT) reverse transcriptaseMore data for this Ligand-Target Pair
LigandBDBM50117090((E,E)-Psammaplin A | 3-(3-Bromo-4-hydroxy-phenyl)-...)
Affinity DataEC50: 5.70E+3nMAssay Description:Activation of PPARgamma (unknown origin) transfected in human MCF7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
LigandBDBM50117090((E,E)-Psammaplin A | 3-(3-Bromo-4-hydroxy-phenyl)-...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis detoxification enzyme mycothiol-S-conjugate amidase (MCA)More data for this Ligand-Target Pair
LigandBDBM50117090((E,E)-Psammaplin A | 3-(3-Bromo-4-hydroxy-phenyl)-...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis detoxification enzyme mycothiol-S-conjugate amidase (MCA)More data for this Ligand-Target Pair
LigandBDBM50117090((E,E)-Psammaplin A | 3-(3-Bromo-4-hydroxy-phenyl)-...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of human recombinant HDAC6 using Boc-lys(Ac)-AMC as substrate preincubated for 20 mins with substrate measured after 60 mins by fluorescen...More data for this Ligand-Target Pair
LigandBDBM50117090((E,E)-Psammaplin A | 3-(3-Bromo-4-hydroxy-phenyl)-...)
Affinity DataIC50: 45nMAssay Description:Inhibition of human recombinant HDAC1 using Boc-lys(Ac)-AMC as substrate preincubated for 20 mins with substrate measured after 60 mins by fluorescen...More data for this Ligand-Target Pair
LigandBDBM50117090((E,E)-Psammaplin A | 3-(3-Bromo-4-hydroxy-phenyl)-...)
Affinity DataIC50: 50nMAssay Description:Inhibition of HDAC in human HeLa cells using Fluor deLys as substrate assessed as deacetylation of substrate by fluorescence assayMore data for this Ligand-Target Pair
LigandBDBM50117090((E,E)-Psammaplin A | 3-(3-Bromo-4-hydroxy-phenyl)-...)
Affinity DataIC50: 50nMAssay Description:Inhibition of HDAC in human HeLa cells using Fluor deLys as substrate assessed as deacetylation of substrate by fluorescence assayMore data for this Ligand-Target Pair
LigandBDBM50117090((E,E)-Psammaplin A | 3-(3-Bromo-4-hydroxy-phenyl)-...)
Affinity DataIC50: 311nMAssay Description:Inhibition of recombinant full length C-terminal FLAG-tagged human HDAC6 expressed in baculovirus infected Sf9 cells using Boc-Lys(Ac)-AMC as substra...More data for this Ligand-Target Pair
LigandBDBM50117090((E,E)-Psammaplin A | 3-(3-Bromo-4-hydroxy-phenyl)-...)
Affinity DataIC50: 12nMAssay Description:Inhibition of C-terminal His-tagged recombinant human HDAC3 (1 to 428 residues)/N-terminal GST-tagged recombinant human NCoR2 (395 to 489 residues) c...More data for this Ligand-Target Pair
LigandBDBM50117090((E,E)-Psammaplin A | 3-(3-Bromo-4-hydroxy-phenyl)-...)
Affinity DataIC50: 33nMAssay Description:Inhibition of recombinant full length C-terminal FLAG-tagged human HDAC2 expressed in baculovirus infected Sf9 cells using Boc-Lys(Ac)-AMC as substra...More data for this Ligand-Target Pair
LigandBDBM50117090((E,E)-Psammaplin A | 3-(3-Bromo-4-hydroxy-phenyl)-...)
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant full length C-terminal FLAG/His-tagged human HDAC1 expressed in baculovirus infected Sf9 cells using Boc-Lys(Ac)-AMC as sub...More data for this Ligand-Target Pair
LigandBDBM50117090((E,E)-Psammaplin A | 3-(3-Bromo-4-hydroxy-phenyl)-...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of Mycothiol -S-conjugate amidase (MCA) from mycobacterium tuberculosisMore data for this Ligand-Target Pair