BDBM50117500 CHEMBL3613624

SMILES CN(C)CC1(CCN(CC1)c1ncnc2[nH]c(C)c(C)c12)C(=O)Nc1cccc(OC(=O)N(C)C)c1

InChI Key InChIKey=PRNCXCNGOBQGGJ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50117500   

TargetLIM domain kinase 1(Homo sapiens (Human))
Amakem Therapeutics

Curated by ChEMBL
LigandPNGBDBM50117500(CHEMBL3613624)
Affinity DataIC50:  22nMAssay Description:Inhibition of LIMK2 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha/beta/gamma(Homo sapiens (Human))
Amakem Therapeutics

Curated by ChEMBL
LigandPNGBDBM50117500(CHEMBL3613624)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of LIMK1 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Amakem Therapeutics

Curated by ChEMBL
LigandPNGBDBM50117500(CHEMBL3613624)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of PKA (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLIM domain kinase 2(Homo sapiens (Human))
Amakem Therapeutics

Curated by ChEMBL
LigandPNGBDBM50117500(CHEMBL3613624)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of ROCK2 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Amakem Therapeutics

Curated by ChEMBL
LigandPNGBDBM50117500(CHEMBL3613624)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of LIMK1 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed