BDBM50117629 CHEMBL3613612

SMILES COC(=O)c1cccc(NC(=O)C2(CN(C)C)CCN(CC2)c2ccnc3[nH]ncc23)c1

InChI Key InChIKey=UMQNZSBIZJEBSD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50117629   

TargetcAMP-dependent protein kinase catalytic subunit alpha/beta/gamma(Homo sapiens (Human))
Amakem Therapeutics

Curated by ChEMBL
LigandPNGBDBM50117629(CHEMBL3613612)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of LIMK1 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Amakem Therapeutics

Curated by ChEMBL
LigandPNGBDBM50117629(CHEMBL3613612)
Affinity DataIC50:  11nMAssay Description:Inhibition of ROCK2 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLIM domain kinase 2(Homo sapiens (Human))
Amakem Therapeutics

Curated by ChEMBL
LigandPNGBDBM50117629(CHEMBL3613612)
Affinity DataIC50:  274nMAssay Description:Inhibition of ROCK2 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLIM domain kinase 1(Homo sapiens (Human))
Amakem Therapeutics

Curated by ChEMBL
LigandPNGBDBM50117629(CHEMBL3613612)
Affinity DataIC50:  65nMAssay Description:Inhibition of PKA (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed