BDBM50119233 CHEMBL101835::{1-[1-(2-Hydroxy-5-oxo-tetrahydro-furan-3-ylcarbamoyl)-3-methyl-butylcarbamoyl]-2-phenyl-ethyl}-carbamic acid benzyl ester

SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(=O)N[C@H]1CC(=O)OC1O

InChI Key InChIKey=NHIDZXMAMOZUNW-GAUDMLSGSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50119233   

TargetCaspase-1(Homo sapiens (Human))
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119233(CHEMBL101835 | {1-[1-(2-Hydroxy-5-oxo-tetrahydro-f...)
Affinity DataIC50:  43nMAssay Description:Inhibitory concentration of compound required against Caspase-1 compared to acylated dipeptidesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-7(Homo sapiens (Human))
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119233(CHEMBL101835 | {1-[1-(2-Hydroxy-5-oxo-tetrahydro-f...)
Affinity DataIC50:  680nMAssay Description:Inhibitory concentration of compound required against Caspase-7 compared to acylated dipeptidesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-8(Homo sapiens (Human))
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119233(CHEMBL101835 | {1-[1-(2-Hydroxy-5-oxo-tetrahydro-f...)
Affinity DataIC50:  8.70E+3nMAssay Description:Inhibitory concentration of compound required against Caspase-8 compared to acylated dipeptidesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119233(CHEMBL101835 | {1-[1-(2-Hydroxy-5-oxo-tetrahydro-f...)
Affinity DataIC50:  137nMAssay Description:Inhibitory concentration of compound required against Caspase-3 compared to acylated dipeptidesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-6(Homo sapiens (Human))
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119233(CHEMBL101835 | {1-[1-(2-Hydroxy-5-oxo-tetrahydro-f...)
Affinity DataIC50:  2.53E+3nMAssay Description:Inhibitory concentration of compound required against Caspase-6 compared to acylated dipeptidesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed