BDBM50119249 4-Methyl-2-(3-naphthalen-1-yl-propionylamino)-pentanoic acid (2-hydroxy-5-oxo-tetrahydro-furan-3-yl)-amide::CHEMBL101448

SMILES CC(C)C[C@H](NC(=O)CCc1cccc2ccccc12)C(=O)N[C@H]1CC(=O)OC1O

InChI Key InChIKey=KYJHBJPEBQLNOM-GVLQVIKUSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50119249   

TargetCaspase-8(Homo sapiens (Human))
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119249(4-Methyl-2-(3-naphthalen-1-yl-propionylamino)-pent...)
Affinity DataIC50:  1.22E+4nMAssay Description:Inhibitory concentration against caspase-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119249(4-Methyl-2-(3-naphthalen-1-yl-propionylamino)-pent...)
Affinity DataIC50:  1.86E+3nMAssay Description:Inhibition of caspase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-7(Homo sapiens (Human))
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119249(4-Methyl-2-(3-naphthalen-1-yl-propionylamino)-pent...)
Affinity DataIC50:  8.77E+3nMAssay Description:Inhibitory concentration against caspase-7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119249(4-Methyl-2-(3-naphthalen-1-yl-propionylamino)-pent...)
Affinity DataIC50:  1.59E+3nMAssay Description:Inhibitory concentration against caspase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-6(Homo sapiens (Human))
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119249(4-Methyl-2-(3-naphthalen-1-yl-propionylamino)-pent...)
Affinity DataIC50:  4.18E+3nMAssay Description:Inhibitory concentration required against caspase-6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed