BDBM50119261 4-Methyl-2-[2-(naphthalen-1-ylamino)-propionylamino]-pentanoic acid (2-hydroxy-5-oxo-tetrahydro-furan-3-yl)-amide::CHEMBL102046

SMILES CC(C)CC(NC(=O)C(C)Nc1cccc2ccccc12)C(=O)N[C@H]1CC(=O)OC1O

InChI Key InChIKey=HHHCHMWEUVMQER-ITHSZLMBSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50119261   

TargetCaspase-7(Homo sapiens (Human))
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119261(4-Methyl-2-[2-(naphthalen-1-ylamino)-propionylamin...)
Affinity DataIC50:  7.24E+3nMAssay Description:Inhibition of Caspase-7 enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-8(Homo sapiens (Human))
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119261(4-Methyl-2-[2-(naphthalen-1-ylamino)-propionylamin...)
Affinity DataIC50:  17nMAssay Description:Inhibition of Caspase-8 enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-6(Homo sapiens (Human))
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119261(4-Methyl-2-[2-(naphthalen-1-ylamino)-propionylamin...)
Affinity DataIC50:  310nMAssay Description:Inhibition of Caspase-6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119261(4-Methyl-2-[2-(naphthalen-1-ylamino)-propionylamin...)
Affinity DataIC50:  512nMAssay Description:Inhibition of Caspase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119261(4-Methyl-2-[2-(naphthalen-1-ylamino)-propionylamin...)
Affinity DataIC50:  87nMAssay Description:Inhibition of Caspase-1 enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed