BDBM50119548 2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-fluoromethyl-phenylamine::CHEMBL143707::N-(2-{[2-amino-4-(fluoromethyl)phenyl]thio}benzyl)-N,N-dimethylamine

SMILES CN(C)Cc1ccccc1Sc1ccc(CF)cc1N

InChI Key InChIKey=OTCJLGGVKHCDCO-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50119548   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50119548(2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-fluorom...)
Affinity DataKi:  1.04nMAssay Description:In vitro displacement of [3H]-paroxetine from human serotonin transporter expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50119548(2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-fluorom...)
Affinity DataKi:  1.10nMAssay Description:In vitro binding affinity of the compound in LLC-PK1 cells by SERT binding assay by using [125I]-IDAM as a radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50119548(2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-fluorom...)
Affinity DataKi:  664nMAssay Description:In vitro displacement of [3H]-nisoxetine from human norepinephrine transporter expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50119548(2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-fluorom...)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro displacement of [3H]-GBR-12,935 from human dopamine transporter expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed