BDBM50119610 CHEMBL3618234
SMILES Cc1nc(N)nc(n1)-c1c(Nc2ccc3ncccc3c2)nc2ccccn12
InChI Key InChIKey=YVIUPILOGILJPD-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50119610
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataKi: 529nMAssay Description:Inhibition of PI3Kalpha (unknown origin) by alpha screen assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataIC50: >780nMAssay Description:Inhibition of PI3Kalpha in human U87MG cells assessed as reduction in AKT Ser473 phosphorylation incubated for 2 hrs followed by compound wahout by a...More data for this Ligand-Target Pair
Affinity DataIC50: 277nMAssay Description:Inhibition of GST-tagged mTOR (1360 to 2549 residues) (unknown origin) using Ulight 4eBP1 peptide incubated for 90 mins by HTRF assayMore data for this Ligand-Target Pair