BDBM50119720 CHEMBL107293::N-{(S)-1-[3-(4-Cyclopropanecarbonyl-phenoxy)-propyl]-pyrrolidin-3-yl}-4-methyl-benzenesulfonamide

SMILES Cc1ccc(cc1)S(=O)(=O)N[C@H]1CCN(CCCOc2ccc(cc2)C(=O)C2CC2)C1

InChI Key InChIKey=PFSYJJKLBNXBAA-NRFANRHFSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50119720   

TargetHistamine H3 receptor(Rattus norvegicus (rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50119720(CHEMBL107293 | N-{(S)-1-[3-(4-Cyclopropanecarbonyl...)
Affinity DataKi:  4.20nMAssay Description:Binding affinity against rat histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H2 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50119720(CHEMBL107293 | N-{(S)-1-[3-(4-Cyclopropanecarbonyl...)
Affinity DataKi:  380nMAssay Description:Binding affinity to the human Histamine H2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50119720(CHEMBL107293 | N-{(S)-1-[3-(4-Cyclopropanecarbonyl...)
Affinity DataKi:  5.50E+3nMAssay Description:Binding affinity to the human Histamine H1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed